Tuberculosis is the single biggest infectious cause of death that kills more HIV-positive people than any other disease. TB is caused by the germ Mycobacterium tuberculosis, which is spread when people who are sick cough near healthy ones. The disease mainly affects the lungs but can spread and affect other body organs. The emergence of new cases, especially in Africa, may be declining, but the progress is slow. New innovative and ambitious technologies are needed, especially at the triaging areas, to identify new TB cases while minimising costs.